Clear cell basal cell carcinoma with neuroendocrine differentiation

Leblebici C., Okcu O., Kelten C., Aksu A. E. K.

TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY, cilt.50, sa.2, ss.73-76, 2016 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 50 Sayı: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.4274/turkderm.01069
  • Dergi Adı: TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.73-76
  • Anahtar Kelimeler: Basal cell carcinoma, neuroendocrine differentiation, clear cell
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Basal cell carcinomas (BCC) are tumors arising from pluripotent stem cells of the epidermis or hair follicles. There are many histological subtypes such as clear cell, a rare variant, and they have the capacity to differentiate towards distinct directions such as neuroendocrine differentiation (NED). An 81-year-old female patient presented with a mass on the lateral side of the right eyebrow. Excisional biopsy was performed. Histopathologic examination revealed clear cell BCC with prominent rosette-like structures suggesting NED. Immunohistochemically, tumor cells were positive for chromogranin and CD56. This is the first reported case of clear cell basal carcinoma with NED.