Association between rs11362 polymorphism in the beta-defensin 1 (DEFB1) gene and dental caries: A meta-analysis

Hatipoglu O., SAYDAM F.

JOURNAL OF ORAL BIOSCIENCES, cilt.62, sa.3, ss.272-279, 2020 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 62 Sayı: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.job.2020.06.004
  • Dergi Adı: JOURNAL OF ORAL BIOSCIENCES
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals
  • Sayfa Sayıları: ss.272-279
  • Anahtar Kelimeler: Caries susceptibility, Dental caries resistance, Human genome, Single nucleotide polymorphism, Meta-analysis, ANTIMICROBIAL PEPTIDES, CLEFT-LIP, SUSCEPTIBILITY, EXPERIENCE, EXPRESSION, CHILDREN
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Objectives: Beta-defensin 1, encoded by the DEFB1 gene, is an important molecule that confers protection from dental caries. Numerous studies have been conducted on the rs11362 polymorphism in the DEFB1 gene. We evaluated the results from studies that have investigated the association between rs11362 polymorphism and dental caries, through a meta-analysis.