Effects of gadolinium-based MRI contrast agents on liver tissue

Mercantepe T., Tumkaya L., Celiker F., Suzan Z. T., Cinar S., Akyildiz K., ...More

JOURNAL OF MAGNETIC RESONANCE IMAGING, vol.48, no.5, pp.1367-1374, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 5
  • Publication Date: 2018
  • Doi Number: 10.1002/jmri.26031
  • Journal Name: JOURNAL OF MAGNETIC RESONANCE IMAGING
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1367-1374
  • Keywords: gadodiamide, gadoteric acid, apoptosis, oxidative stress, liver, rat, OXIDATIVE STRESS, TOXICITY, CHLORIDE, RETENTION
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

BackgroundPurposeMRI with contrast is often used clinically. However, recent studies have reported a high accumulation of gadolinium-based contrast agents (GBCAs) in kidney, liver, and spleen tissues in several mouse models.