Melatonin ameliorates periodontitis related inflammatory stress at cardiac left ventricular tissues in rats

KÖSE, OĞUZ; Bayraktar, Sevda; AKYILDIZ, KERİMALİ; ALTIN, AHMET; ARABACI, TANER; YEMENOĞLU, HATİCE; Korkmaz, MELTEM; KÖSE, TAHA; Sener, Leyla; MERCANTEPE, TOLGA; TÜMKAYA, LEVENT; YILMAZ, ADNAN

doi:10.1002/jper.19-0685

Melatonin ameliorates periodontitis related inflammatory stress at cardiac left ventricular tissues in rats

KÖSE O. , Bayraktar S. K. , AKYILDIZ K. , ALTIN A. , ARABACI T., YEMENOĞLU H. , ...More

JOURNAL OF PERIODONTOLOGY, vol.91, no.11, pp.1486-1494, 2020 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 91 Issue: 11
Publication Date: 2020
Doi Number: 10.1002/jper.19-0685
Title of Journal : JOURNAL OF PERIODONTOLOGY
Page Numbers: pp.1486-1494
Keywords: cardiovascular disease(s), experimental periodontitis, matrix metalloproteinase(s), melatonin, oxidative stress, periodontal-systemic disease interactions, ALVEOLAR BONE LOSS, OXIDATIVE STRESS, HEART-FAILURE, ANTIOXIDANT, INDEX, HYPERTROPHY, DYSFUNCTION, MECHANISMS, INDUCTION, DAMAGE

Abstract

BackgroundThe aim of this experimental rat study was to investigate the potential inflammatory effects of periodontitis on cardiac left ventricular tissue and the therapeutic activity of melatonin on these effects.