The relationship of plasma catestatin concentrations with metabolic and vascular parameters in untreated hypertensive patients: Influence on high-density lipoprotein cholesterol

Durakoglugil M. E., AYAZ T., KOCAMAN S. A., KIRBAS A., DURAKOGLUGIL T., ERDOGAN T., ...Daha Fazla

ANATOLIAN JOURNAL OF CARDIOLOGY, cilt.15, sa.7, ss.577-585, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 7
  • Basım Tarihi: 2015
  • Doi Numarası: 10.5152/akd.2014.5536
  • Dergi Adı: ANATOLIAN JOURNAL OF CARDIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.577-585
  • Anahtar Kelimeler: catestatin, hypertension, high-density lipoprotein cholesterol, sympatho-adrenal flow, low HDL-C, INHIBITORY PEPTIDE CATESTATIN, CHROMOGRANIN-A FRAGMENT, CATECHOLAMINE RELEASE, IN-VIVO, A(352-372), HUMANS, SYSTEM, ARTERY, RISK
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Objective: Catestatin has several cardiovascular actions, in addition to diminished sympatho-adrenal flow. Decreased plasma catestatin levels may reflect a predisposition for the development of hypertension and metabolic disorders. We planned to investigate the possible roles of catestatin in untreated hypertensive patients. As a secondary objective, we compared catestatin concentrations of healthy subjects with those of hypertensive patients in order to understand whether catestatin is increased reactively or diminished at onset.