The effect of rocuronium, sugammadex, and their combination on cardiac muscle and diaphragmatic skeletal muscle cells

Kalkan Y., BOSTAN H., TÜMKAYA L., TOMAK Y., Bostan M., YILMAZ A., ...Daha Fazla

JOURNAL OF ANESTHESIA, cilt.26, sa.6, ss.870-877, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 6
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1007/s00540-012-1440-4
  • Dergi Adı: JOURNAL OF ANESTHESIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.870-877
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Rocuronium has been associated with muscle weakness when administered in prolonged infusions. The effect of sugammadex and rocuronium together on muscle is unknown. In this study, we examined the effects of rocuronium and sugammadex, and the complex formed by these agents, on cardiac and diaphragmatic muscle cells.