Emergency coronary bypass surgery in patients under the influence of dual antiplatelet therapy: effects of tranexamic acid and desmopressin acetate


ALTUN G., Hemsinli D. , PULATHAN Z., Civelek A.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.47, no.6, pp.1708-1714, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 6
  • Publication Date: 2017
  • Doi Number: 10.3906/sag-1612-140
  • Title of Journal : TURKISH JOURNAL OF MEDICAL SCIENCES
  • Page Numbers: pp.1708-1714
  • Keywords: Clopidogrel, coronary bypass surgery, desmopressin acetate, dual antiplatelet therapy, tranexamic acid, CARDIOPULMONARY BYPASS, DOUBLE-BLIND, BLOOD-LOSS, CLOPIDOGREL, TRANSFUSIONS, ASPIRIN

Abstract

Background/aim: Bleeding in patients undergoing coronary artery bypass grafting (CABG) while using dual antiplatelet therapy (DAPT) is a cause of significant morbidity and mortality. The aim of this study is to examine the perioperative hemostatic effects of tranexamic acid (TnX-A) and desmopressin acetate (Des) in these patients.