PD-1 and PD-L2 expression predict relapse risk and poor survival in patients with stage III colorectal cancer

Zengin M., Zergeroglu S., Okcu O., Benek S.

CELLULAR ONCOLOGY, cilt.44, sa.2, ss.423-432, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1007/s13402-020-00579-5
  • Dergi Adı: CELLULAR ONCOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, Biotechnology Research Abstracts, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.423-432
  • Anahtar Kelimeler: Colorectal cancer, PD-1, PDL-2, Prognostic biomarkers, Stage III
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Background Immune responses have long been an area of interest in cancer research. In this study, the effects of programmed cell death-1 (PD-1) and its ligand (PD-L2) on the prognosis of colorectal cancer (CRC) were investigated.