CHEMICO-BIOLOGICAL INTERACTIONS, vol.258, pp.266-275, 2016 (Journal Indexed in SCI)
Article / Article
Title of Journal :
Aliskiren, Cytokine, Indomethacin, Renin angiotensin aldestron system, Ulcer, SMOOTH-MUSCLE-CELLS, NONSTEROIDAL ANTIINFLAMMATORY DRUGS, OXIDATIVE STRESS, RECEPTOR ANTAGONIST, INDUCED LESIONS, MUCOSAL DAMAGE, NITRIC-OXIDE, INFLAMMATION, TELMISARTAN, PROTECTS
Purpose: Previously blocking the renin angiotensin system (RAAS) has been effective in the prevention of gastric damage. Therefore, the aim of this study was to investigate the effects of aliskiren, and thus, direct renin blockage, in indomethacin-induced gastric damage model.