Effects of topiramate on adipocyte differentiation and gene expression of certain carbonic anhydrase isoenzymes

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SÜMER A., Keha E. E., MENTEŞE A., ALVER A.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.45, no.2, 2020 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 45 Issue: 2
• Publication Date: 2020
• Doi Number: 10.1515/tjb-2019-0067
• Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, TR DİZİN (ULAKBİM)
• Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Background: Topiramate, an antiepileptic drug, besides its known effects in neurons, is a carbonic anhydrase inhibitor and causes weight loss in treated subjects, but, the mechanisms of weight loss effect have not been yet identified..