Elevated serum YKL-40 level predicts myocardial reperfusion and in-hospital MACE in patients with STEMI

CETIN M., KOCAMAN S. A., CANGA A., KIRBAS A., YILMAZ A., Erdoğan T., ...Daha Fazla

HERZ, cilt.38, sa.2, ss.202-209, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 2
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1007/s00059-012-3671-4
  • Dergi Adı: HERZ
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.202-209
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Macrophages in atherosclerotic plaques secrete YKL-40, a new biomarker of acute and chronic inflammation in patients with stable CAD. We hypothesized that YKL-40 may be a specific marker reflecting the burden of localized inflammation in myocardium and a predictor in patients with STEMI. In this study, we investigated the relationship of YKL-40 to in-hospital major adverse cardiac events (MACE), reperfusion parameters and its predictors in patients with STEMI.