Elevated serum YKL-40 level predicts myocardial reperfusion and in-hospital MACE in patients with STEMI

CETIN M., KOCAMAN S. A., CANGA A., KIRBAS A., YILMAZ A., Erdoğan T., ...More

HERZ, vol.38, no.2, pp.202-209, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 2
  • Publication Date: 2013
  • Doi Number: 10.1007/s00059-012-3671-4
  • Journal Name: HERZ
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.202-209
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Macrophages in atherosclerotic plaques secrete YKL-40, a new biomarker of acute and chronic inflammation in patients with stable CAD. We hypothesized that YKL-40 may be a specific marker reflecting the burden of localized inflammation in myocardium and a predictor in patients with STEMI. In this study, we investigated the relationship of YKL-40 to in-hospital major adverse cardiac events (MACE), reperfusion parameters and its predictors in patients with STEMI.