Elevated serum YKL-40 level predicts myocardial reperfusion and in-hospital MACE in patients with STEMI

CETIN M. , KOCAMAN S. A. , CANGA A., KIRBAS A., YILMAZ A. , Erdoğan T. , ...Daha Fazla

HERZ, cilt.38, sa.2, ss.202-209, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 38 Konu: 2
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1007/s00059-012-3671-4
  • Dergi Adı: HERZ
  • Sayfa Sayıları: ss.202-209


Macrophages in atherosclerotic plaques secrete YKL-40, a new biomarker of acute and chronic inflammation in patients with stable CAD. We hypothesized that YKL-40 may be a specific marker reflecting the burden of localized inflammation in myocardium and a predictor in patients with STEMI. In this study, we investigated the relationship of YKL-40 to in-hospital major adverse cardiac events (MACE), reperfusion parameters and its predictors in patients with STEMI.