Elevated serum YKL-40 level predicts myocardial reperfusion and in-hospital MACE in patients with STEMI

CETIN M. , KOCAMAN S. A. , CANGA A., KIRBAS A., YILMAZ A. , Erdoğan T. , ...More

HERZ, vol.38, no.2, pp.202-209, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 2
  • Publication Date: 2013
  • Doi Number: 10.1007/s00059-012-3671-4
  • Title of Journal : HERZ
  • Page Numbers: pp.202-209


Macrophages in atherosclerotic plaques secrete YKL-40, a new biomarker of acute and chronic inflammation in patients with stable CAD. We hypothesized that YKL-40 may be a specific marker reflecting the burden of localized inflammation in myocardium and a predictor in patients with STEMI. In this study, we investigated the relationship of YKL-40 to in-hospital major adverse cardiac events (MACE), reperfusion parameters and its predictors in patients with STEMI.