Marine-Lenhart syndrome with papillary thyroid carcinoma


Atmaca H., Colak R., Yazici Z. A. , Kefeli M., Tosun F. C.

JOURNAL OF RESEARCH IN MEDICAL SCIENCES, vol.20, no.4, pp.412-415, 2015 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 4
  • Publication Date: 2015
  • Title of Journal : JOURNAL OF RESEARCH IN MEDICAL SCIENCES
  • Page Numbers: pp.412-415

Abstract

Graves' disease with accompanying functioning nodules is known as Marine-Lenhart syndrome. Autonomously functioning thyroid nodules (AFTNs) also within Graves' thyroid tissue are almost always bening in nature. A 45-year-old man developed hyperthyroidism due to the coexistence of Graves' disease and AFTN. Total thyroidectomy was performed. The hyperfunctioning nodule with centrally hypoactive foci detected by technetium-99m thyroid scanning was histologically diagnosed as papillary thyroid carcinoma that was 2.5 cm in diameter. We report the presence of papillary thyroid carcinoma within AFTN in patients with Marine-Lenhart syndrome, which has not been reported so far.