Melatonin causes regression of endometriotic implants in rats by modulating angiogenesis, tissue levels of antioxidants and matrix metalloproteinases

Yilmaz B., Kilic S., Aksakal O., Ertas I. E., Tanrisever G. G., BAYAZIT Y., ...Daha Fazla

ARCHIVES OF GYNECOLOGY AND OBSTETRICS, cilt.292, sa.1, ss.209-216, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 292 Sayı: 1
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1007/s00404-014-3599-4
  • Dergi Adı: ARCHIVES OF GYNECOLOGY AND OBSTETRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.209-216
  • Anahtar Kelimeler: Melatonin, Rat endometriosis, SOD, MDA, VEGF, MMP-9, TIMP-2, ENDOTHELIAL GROWTH-FACTOR, ESTROGEN-RECEPTOR, EXPRESSION, EXPLANTS, MODEL, ESTABLISHMENT, PROTECTION, INHIBITORS, PROTEIN
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Hayır

Özet

Purpose The aim of this study was to test if melatonin causes regression of endometriotic implants and whether it influences implant levels of superoxide dismutase (SOD), malondialdehyde (MDA), vascular endothelial growth factor (VEGF), tissue inhibitor of metalloproteinase (TIMP)-2 and matrix metalloproteinase (MMP)-9 in rats.