A pilot study of Helicobacter pylori genotypes and cytokine gene polymorphisms in reflux oesophagitis and peptic ulcer disease

Akdogan, REMZİ; ÖZGÜR, ORHAN; Gucuyeter, S.; KAKLIKKAYA, NEŞE; ÇOBANOĞLU, ÜMİT; AYDİN, FARUK

doi:10.4149/bll_2014_046

A pilot study of Helicobacter pylori genotypes and cytokine gene polymorphisms in reflux oesophagitis and peptic ulcer disease

Akdogan R. A. , ÖZGÜR O., Gucuyeter S., KAKLIKKAYA N., ÇOBANOĞLU Ü., AYDİN F.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.115, no.4, pp.221-228, 2014 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 115 Issue: 4
Publication Date: 2014
Doi Number: 10.4149/bll_2014_046
Title of Journal : BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
Page Numbers: pp.221-228

Abstract

Helicobacter pylon causes various diseases such as chronic gastritis, peptic ulcer and gastric cancer. While majority of the people infected with H. pylori is asymptomatic, 15-20 % of them develop such diseases. The main factors, which determine the development of H. pylori related diseases might be bacterial virulence, host genetic and environmental factors.