A pilot study of Helicobacter pylori genotypes and cytokine gene polymorphisms in reflux oesophagitis and peptic ulcer disease

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Akdogan R. A. , ÖZGÜR O., Gucuyeter S., KAKLIKKAYA N., ÇOBANOĞLU Ü., AYDİN F.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.115, no.4, pp.221-228, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 115 Issue: 4
  • Publication Date: 2014
  • Doi Number: 10.4149/bll_2014_046
  • Title of Journal : BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Page Numbers: pp.221-228
  • Keywords: Helicobacter pylori genotypes, single nucleotide polymorphisms, reflux oesophagitis, peptic ulcer, DUODENAL-ULCER, GASTRIC-CANCER, INCREASED RISK, CLINICAL-RELEVANCE, INFECTION, CAGA, ICEA, VACA, ERADICATION, STRAINS

Abstract

Helicobacter pylon causes various diseases such as chronic gastritis, peptic ulcer and gastric cancer. While majority of the people infected with H. pylori is asymptomatic, 15-20 % of them develop such diseases. The main factors, which determine the development of H. pylori related diseases might be bacterial virulence, host genetic and environmental factors.