Green Protocol: Solvent- and Catalyst-Free Synthesis of Benzimidazole Derivatives via Microwave Technique

Mentese E., DOĞAN İ. S., KAHVECİ B.

CHEMISTRY OF HETEROCYCLIC COMPOUNDS, vol.49, no.8, pp.1136-1140, 2013 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 8
  • Publication Date: 2013
  • Doi Number: 10.1007/s10593-013-1354-6
  • Journal Name: CHEMISTRY OF HETEROCYCLIC COMPOUNDS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1136-1140
  • Keywords: 2-[(alkyl/aryl)(ethoxy)methylidene]hydrazinecarboxylate, 2-substituted benzimidazole, catalyst-free reaction, microwaves, solvent-free reaction, IN-VITRO, EFFICIENT SYNTHESIS, ASSISTED SYNTHESIS
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

A simple and green protocol has been developed for the synthesis of benzimidazoles. In this protocol, 2-[(alkyl/aryl)(ethoxy)methylidene]hydrazinecarboxylates with 1,2-phenylenediamine derivatives under solvent- and catalyst-free conditions under microwave irradiation lead to products with good yields in short reaction times.