4-(4-(( 5-Amino-1,3,4-thiadiazol-2-yl)methoxy) phenyl)-1-(( 5-amino-1,3,4-thiadiazol-2-yl)methyl)-3-benzyl-1H-1,2,4-triazol-5( H)-one: Synthesis, Characterization and Computational Studies


Unluer D., ÜNVER Y., Dugdu E., Akcay H. T. , SANCAK K.

LETTERS IN ORGANIC CHEMISTRY, cilt.13, ss.604-617, 2016 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 13 Konu: 8
  • Basım Tarihi: 2016
  • Doi Numarası: 10.2174/1570178613666160930121719
  • Dergi Adı: LETTERS IN ORGANIC CHEMISTRY
  • Sayfa Sayıları: ss.604-617

Özet

Background: 1,2,4-triazole and its derivatives are known to have various biological activities such as antifungal, antiviral, antidepressant, antitumor, anti-inflammatory, antitubercular, antimigrain and anti-cancer. Computational chemistry plays an important role in determining structural and chemical properties of chemical compounds. There are many studies on computational studies of triazole derivatives. The aim of this study is to prepare new triazole derivative having potent of bio-active material and to investigate the computational properties.