Microwave-assisted preparation of azachalcones and their N-alkyl derivatives with antimicrobial activities
NATURAL PRODUCT RESEARCH, cilt.28, sa.7, ss.483-487, 2014 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 28 Sayı: 7
- Basım Tarihi: 2014
- Doi Numarası: 10.1080/14786419.2013.879472
- Dergi Adı: NATURAL PRODUCT RESEARCH
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.483-487
- Anahtar Kelimeler: microwave synthesis, azachalcone, antimicrobial activities, N-alkyl azachalconium bromide, CHALCONES
- Recep Tayyip Erdoğan Üniversitesi Adresli: Evet
Özet
Two new azachalcones were prepared by both Claisen-Schmidt condensation and a simple environmentally trendy microwave-assisted method. Ten new N-alkyl (C-6,C-8,C-10,C-12,C-14)-substituted azachalconium bromides (3a-e, 4a-e) were prepared from compounds 1 and 2 with corresponding alkyl halides. The antimicrobial activities of all the compounds were tested against Enterococcus faecalis, Yersinia pseudotuberculosis, Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus micro-organisms.