The effects of TNF-alpha inhibitors on carbon tetrachloride-induced nephrotoxicity

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Ozdemir A., Tumkaya L., Kalcan S., Uyan M., Karakaya A., Demiral G., ...Daha Fazla

CLINICAL AND EXPERIMENTAL HYPERTENSION, cilt.44, sa.3, ss.291-296, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 3
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1080/10641963.2021.2018600
  • Dergi Adı: CLINICAL AND EXPERIMENTAL HYPERTENSION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.291-296
  • Anahtar Kelimeler: Cleaved caspase-3, kidney, serum BUN, serum creatinine TNF-alpha inhibitors, TNF-beta, INFLIXIMAB, KIDNEY, INJURY
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Objectives: Carbon tetrachloride (CCl4), employed in various industrial fields, can cause acute damage in renal tissues. This study investigated the therapeutic effect of the TNF-alpha inhibitor Infliximab on TGF-beta and apoptosis caused by acute kidney image induced by CCl4.