Retrospective analysis of the histopathological results of operative hysteroscopy performed in a tertiary healthcare facility over a 3-year period.
Medicine Science, cilt.15, sa.2, ss.929-933, 2026 (TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 15 Sayı: 2
- Basım Tarihi: 2026
- Doi Numarası: 10.5455/medscience.2025.12.339
- Dergi Adı: Medicine Science
- Derginin Tarandığı İndeksler: TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.929-933
- Recep Tayyip Erdoğan Üniversitesi Adresli: Evet
Özet
Operative hysteroscopy allows direct visualization and targeted treatment of intrauterine pathologies. This study evaluated the clinical indications and histopathological outcomes of operative hysteroscopy performed over a three-year period in a tertiary healthcare facility, with particular attention to differences between premenopausal and postmenopausal patients. This retrospective study included 211 consecutive patients who underwent operative hysteroscopy for suspected intrauterine pathology between July 2019 and July 2022. Patients were classified as premenopausal or postmenopausal. Clinical indications, demographic characteristics, and histopathological findings were obtained from medical records and analyzed comparatively between groups. Of the 211 patients, 184 (87.2%) were premenopausal and 27 (12.8%) were postmenopausal. The mean age was significantly higher in postmenopausal patients compared with premenopausal patients (58.15 ± 6.22 vs. 41.96 ± 7.47 years, p<0.001). The most common indication for hysteroscopy was ultrasonographic suspicion of endometrial pathology (49.8%), followed by abnormal uterine bleeding (22.3%). Endometrial polyps were the most frequent histopathological finding (n=113, 53.6%). Malignant and premalignant lesions were identified in 14 patients (6.6%) and were significantly more common in postmenopausal than in premenopausal patients (22.2% vs. 4.3%, p=0.004). All cases of endometrial carcinoma presented with postmenopausal or abnormal uterine bleeding. Endometrial polyps are the most common histopathological finding in patients undergoing operative hysteroscopy, especially among those with abnormal uterine bleeding or suspicious ultrasonographic findings. Although malignant lesions are relatively uncommon, their significantly higher prevalence in postmenopausal patients highlights the importance of careful hysteroscopic evaluation and targeted endometrial sampling in this population.