Topiramate has protective effect on renal injury

Cure M. C., Cure E., TÜMKAYA L., Kalkan Y., Aydin I., Kirbas A., ...Daha Fazla

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.116, sa.4, ss.259-263, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 116 Sayı: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.4149/bll_2015_050
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.259-263
  • Anahtar Kelimeler: topiramate, ischemia reperfusion, kidney, carbonic anhydrase II, ISCHEMIA-REPERFUSION INJURY, CARBONIC-ANHYDRASE-III, ANTIEPILEPTIC DRUGS, CELLS, ISCHEMIA/REPERFUSION, ERYTHROPOIETIN, ANTIOXIDANT, INHIBITION
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Background: Topiramate (TPM) decreases tumor necrosis factor-alpha (TNF-alpha) and oxidative stress. We investigated protective effects of TPM on cell damage in kidney tissue during ischemia-reperfusion (I/R) damage.