Topiramate has protective effect on renal injury

Cure, MEDİNE; Cure, ERKAN; TÜMKAYA, LEVENT; Kalkan, YILDIRAY; Aydin, İBRAHİM; Kirbas, AYNUR; Efe, HASAN; Sehitoglu, İBRAHİM; YÜCE, Süleyman

doi:10.4149/bll_2015_050

Topiramate has protective effect on renal injury

Cure M. C., Cure E., TÜMKAYA L., Kalkan Y., Aydin I., Kirbas A., ...More

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.116, no.4, pp.259-263, 2015 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 116 Issue: 4
Publication Date: 2015
Doi Number: 10.4149/bll_2015_050
Journal Name: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.259-263
Keywords: topiramate, ischemia reperfusion, kidney, carbonic anhydrase II, ISCHEMIA-REPERFUSION INJURY, CARBONIC-ANHYDRASE-III, ANTIEPILEPTIC DRUGS, CELLS, ISCHEMIA/REPERFUSION, ERYTHROPOIETIN, ANTIOXIDANT, INHIBITION
Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Background: Topiramate (TPM) decreases tumor necrosis factor-alpha (TNF-alpha) and oxidative stress. We investigated protective effects of TPM on cell damage in kidney tissue during ischemia-reperfusion (I/R) damage.