Coronary flow reserve is impaired in patients with nonalcoholic fatty liver disease: Association with liver fibrosis

YILMAZ Y., Kurt R., Yonal O., Polat N., ÇELİKEL Ç., Gurdal A., ...More

ATHEROSCLEROSIS, vol.211, no.1, pp.182-186, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 211 Issue: 1
  • Publication Date: 2010
  • Doi Number: 10.1016/j.atherosclerosis.2010.01.049
  • Journal Name: ATHEROSCLEROSIS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.182-186
  • Keywords: Transthoracic Doppler harmonic echocardiography, Coronary flow reserve, Nonalcoholic fatty liver disease, Liver biopsy, SERUM ADIPONECTIN LEVELS, INTIMA-MEDIA THICKNESS, ENDOTHELIAL DYSFUNCTION, HYPERTENSIVE PATIENTS, METABOLIC SYNDROME, ABNORMALITIES
  • Recep Tayyip Erdoğan University Affiliated: No

Abstract

Background: Nonalcoholic fatty liver disease (NAFLD) is associated with an increased risk of cardiovascular disease. Coronary flow reserve (CFR) is widely used to examine the integrity of coronary microvascular circulation. We evaluated the prevalence of impaired CFR in patients with biopsy-proven NAFLD. We also investigated the independent clinical, biochemical, and liver histology predictors of CFR in the setting of NAFLD.