The Importance of Cytokeratin 19 Expression in the Differentiation of Basal Cell Carcinoma and Trichoepithelioma

Bedir R., Şehıtoğlu I., Yurdakul C., Saygın İ., Üstüner P., Dilek N.

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, cilt.9, sa.1, 2015 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9 Sayı: 1
  • Basım Tarihi: 2015
  • Doi Numarası: 10.7860/jcdr/2015/10915.5414
  • Dergi Adı: JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, Directory of Open Access Journals
  • Anahtar Kelimeler: Differential diagnosis, Follicular germinative cells, Hair buds, Immunohistochemistry, Skin tumour
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Introduction: Basal cell carcinoma (BCC) is the most common skin neoplasm reported in human. On the other hand, trichoepithelioma (TE) is a rare, benign tumour of skin adnexa. The differentiation of BCC and TE may be difficult since their morphological findings are similar. In a few studies, it has been determined that undifferentiated basaloid cells are highly positively stained with cytokeratin 19.