The Importance of Cytokeratin 19 Expression in the Differentiation of Basal Cell Carcinoma and Trichoepithelioma
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, vol.9, no.1, 2015 (ESCI, Scopus)
- Publication Type: Article / Article
- Volume: 9 Issue: 1
- Publication Date: 2015
- Doi Number: 10.7860/jcdr/2015/10915.5414
- Journal Name: JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
- Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, Directory of Open Access Journals
- Keywords: Differential diagnosis, Follicular germinative cells, Hair buds, Immunohistochemistry, Skin tumour
- Recep Tayyip Erdoğan University Affiliated: Yes
Abstract
Introduction: Basal cell carcinoma (BCC) is the most common skin neoplasm reported in human. On the other hand, trichoepithelioma (TE) is a rare, benign tumour of skin adnexa. The differentiation of BCC and TE may be difficult since their morphological findings are similar. In a few studies, it has been determined that undifferentiated basaloid cells are highly positively stained with cytokeratin 19.