EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, vol.18, no.14, pp.2076-2083, 2014 (Journal Indexed in SCI)
Article / Article
Title of Journal :
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
Cisplatin, Intestinal toxicity, Infliximab, Protective effects, RAT SMALL-INTESTINE, SUPEROXIDE-DISMUTASE, INDUCED APOPTOSIS, ALPHA THERAPY, CHEMOTHERAPY, INDUCTION, INJURY, MODEL
OBJECTIVE: Cisplatin (CP) is a popular chemotherapeutic agent. However, high doses of CP may lead to severe side effects to the gastrointestinal system. The aim of this study was to investigate the protective effects of infliximab on small intestine injury induced by high doses of CP.