Carbonic anhydrase I and II autoantibodies in Behcet's disease

MENTEŞE A., ALVER A., DEMİR S., Sumer A., Yaman S O., KARKUCAK M., ...Daha Fazla

ACTA REUMATOLOGICA PORTUGUESA, cilt.42, sa.1, ss.26-31, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42 Sayı: 1
  • Basım Tarihi: 2017
  • Dergi Adı: ACTA REUMATOLOGICA PORTUGUESA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.26-31
  • Anahtar Kelimeler: Autoantibody, Behcet's disease, Carbonic anhydrase, OXIDATIVE STRESS, ANTIBODIES, AUTOIMMUNITY
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Background: Behcet's disease ( BD) is a vasculitis, seen more frequently around the Mediterranean and the Far East, and evinces with oral and genital ulcerations, skin lesions and uveitis. Carbonic anhydrase ( CA) is a metalloenzyme which is widely distributed in the living world, and it is essential for the regulation of acid-base balance. Anti-CA antibodies have been reported in many disorders, such as systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, endometriosis, idiopathic chronic pancreatitis, type 1 diabetes and Graves' disease. The goal of this study was to investigate CA I and II autoantibodies in BD.