The development of chronic myelogenous leukemia in a patient with malign fibrous histiositom treated with radiotherapy: Case report

Akdogan E. , SÖNMEZ M., YILMAZ M., Durmus A., Ovali E., Omay S. B.

UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI, cilt.18, sa.2, ss.116-120, 2008 (SCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Konu: 2
  • Basım Tarihi: 2008
  • Sayfa Sayıları: ss.116-120


Thirty three years old women was treated with surgery and subsequent radiotherapy for diagnosis of malign fibrous histiosarcom (MFH) on left upper leg. She achived complete remission. 6 years later asymptomatic leukocytosis occured. Analysis using RT-PCR did show bcr-abl transcript. She was diagnosed chronic myelogenous leukemia (CML). Secondary malignancy like CML is one of the rare late complication of radiotherapy. We report here, a case who is diagnosed CML 6 years later after treatment with radiotherapy.