EFFICIENT MICROWAVE-ASSISTED SYNTHESIS OF N-(2-ALKYL/ARYL-4-PHENYL-1H-IMIDAZOL-1-YL)-2-PHENYLACETAMIDES


Mentes E. , Yilmaz F.

SYNTHETIC COMMUNICATIONS, vol.44, no.16, pp.2348-2354, 2014 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 16
  • Publication Date: 2014
  • Doi Number: 10.1080/00397911.2014.895382
  • Title of Journal : SYNTHETIC COMMUNICATIONS
  • Page Numbers: pp.2348-2354

Abstract

An easy, efficient, and environmentally friendly method for the synthesis of N-(2-alkyl/aryl-4-phenyl-1H-imidazol-1-yl)-2-phenylacetamides from the reaction of phenyl acylbromides and phenylacetohydrazide derivatives has been presented. Shorter reaction times, simple workup procedure, no catalyst requirement, and use of small quantities of organic solvent are the most obvious advantages of this protocol.