Target peptide recognition by S100P protein and role of central linker region and dimer interface

TUTAR Y.

Protein and Peptide Letters, cilt.13, sa.3, ss.307-311, 2006 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13 Sayı: 3
  • Basım Tarihi: 2006
  • Doi Numarası: 10.2174/092986606775338380
  • Dergi Adı: Protein and Peptide Letters
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.307-311
  • Anahtar Kelimeler: Conformational change, Peptide binding, S100P
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Hayır

Özet

Interaction between S100P and its target protein is an essential step in several cellular functions. The amphiphatic mellitin peptide binds tightly to S100P protein in the presence of calcium cation. Since little is known about the recognition sequence, mellitin interaction form a model for S100P. Interaction between mellitin and protein examined to identify key regions required for the protein-protein interaction. © 2006 Bentham Science Publishers Ltd.