BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.110, no.1, pp.3-6, 2009 (SCI-Expanded)
Background: Patients with cancer are frequently treated with anticoagulants, including heparin, to prevent or to treat the deep vein thrombosis. It has been indicated that heparin affects the survival of patients with cancer. Also, the apoptotic and antiproliferative effects of heparin on some cancers has been demonstrated. Experimental studies support the hypothesis that cancer progression can be influenced by heparin, but the results of these studies are not conclusive.