The effects of heparin on DLD-1 colon cancer cell line

UZUN Y., Akdogan E., ÖZDEMİR F., Ovali E.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.110, no.1, pp.3-6, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 110 Issue: 1
  • Publication Date: 2009
  • Journal Name: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.3-6
  • Recep Tayyip Erdoğan University Affiliated: No

Abstract

Background: Patients with cancer are frequently treated with anticoagulants, including heparin, to prevent or to treat the deep vein thrombosis. It has been indicated that heparin affects the survival of patients with cancer. Also, the apoptotic and antiproliferative effects of heparin on some cancers has been demonstrated. Experimental studies support the hypothesis that cancer progression can be influenced by heparin, but the results of these studies are not conclusive.