Caspase-cleaved fragments of cytokeratin 18 in patients with chronic hepatitis B
CLINICA CHIMICA ACTA, cilt.411, ss.2029-2032, 2010 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 411
- Basım Tarihi: 2010
- Doi Numarası: 10.1016/j.cca.2010.08.035
- Dergi Adı: CLINICA CHIMICA ACTA
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.2029-2032
- Recep Tayyip Erdoğan Üniversitesi Adresli: Hayır
Özet
Background: During hepatocyte apoptosis, intermediate filament protein cytokeratin 18 is cleaved by caspases at Asp396 which can be specifically detected by the monoclonal antibody M30 (M30-antigen). In this study, we sought to determine whether serum M30-antigen levels can serve as a useful biomarker of liver injury in the clinical spectrum of HBV infection.