Uncovering a New Cause of Obstructive Hydrocephalus Following Subarachnoid Hemorrhage: Choroidal Artery Vasospasm-Related Ependymal Cell Degeneration and Aqueductal Stenosis-First Experimental Study


Yolas C., Ozdemir N. G. , Kanat A., AYDIN M. D. , Keles P., Kepoglu U., ...More

WORLD NEUROSURGERY, vol.90, pp.484-491, 2016 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 90
  • Publication Date: 2016
  • Doi Number: 10.1016/j.wneu.2016.03.049
  • Journal Name: WORLD NEUROSURGERY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.484-491
  • Keywords: Aqueductal stenosis, Choroidal artery vasospasm, Ependymal cell desquamation, Hydrocephalus, Subarachnoid hemorrhage, GLOSSOPHARYNGEAL NERVE, GANGLION DEGENERATION, 1ST REPORT, PLEXUS, PATHOPHYSIOLOGY, VESICLES, NUMBER, MODEL, TRIAL

Abstract

BACKGROUND: Hydrocephalus is a serious complication of subarachnoid hemorrhage (SAH). Obstruction of the cerebral aqueduct may cause hydrocephalus after SAH. Although various etiologic theories have been put forward, choroidal artery vasospasm-related ependymal desquamation and subependymal basal membrane rupture as mechanisms of aqueductal stenosis have not been suggested in the literature.