Is resveratrol a potential substitute for leuprolide acetate in experimental endometriosis?

Tekin, YEŞİM; GÜVEN, SÜLEYMAN; Kirbas, AYNUR; Kalkan, YILDIRAY; Tumkaya, LEVENT; GUVEN, Emine

doi:10.1016/j.ejogrb.2014.10.041

Is resveratrol a potential substitute for leuprolide acetate in experimental endometriosis?

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Tekin Y. B., GÜVEN S., Kirbas A., Kalkan Y., Tumkaya L., GUVEN E. S. G.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, vol.184, pp.1-6, 2015 (SCI-Expanded)

Publication Type: Article / Article
Volume: 184
Publication Date: 2015
Doi Number: 10.1016/j.ejogrb.2014.10.041
Journal Name: EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1-6
Keywords: Endometriosis, Rat model, Resveratrol, Leuprolide acetate, Treatment, RAT MODEL, REGRESSION, TISSUE, INVASIVENESS, ANGIOGENESIS, INFLAMMATION, INHIBITOR, EXPLANTS, IMMUNE
Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Objective: Resveratrol, a phytoalexin polyphenol, has anti-angiogenic, antioxidant, anti-inflammatory properties. We aimed to compare the anti-inflammatory and anti-angiogenic effects of resveratrol and leuprolide acetate (LA) in an experimental endometriosis model.