The Relationship of Mitral Anular Calcification with Mortality and Myocardial Injury in COVID-19 Patients

Creative Commons License

OZER S., bulut e., Aydın E., HAZNEDAR KIRCI D., Özyıldız A. G., Peker M., ...More

Sakarya Tıp Dergisi, vol.12, no.3, pp.544-551, 2022 (Peer-Reviewed Journal) identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 3
  • Publication Date: 2022
  • Doi Number: 10.31832/smj.1126067
  • Journal Name: Sakarya Tıp Dergisi
  • Journal Indexes: TR DİZİN (ULAKBİM)
  • Page Numbers: pp.544-551
  • Recep Tayyip Erdoğan University Affiliated: Yes


Objective: Coronavirus disease-2019 (COVID-19) can particularly affect the respiratory and cardiovascular systems and cause serious mortality. Mitral annular calcification (MAC) is a mitral valve pathology associated with cardiac mortality. We aimed to evaluate the effect of MAC on myocardial injury (MI) and mortality, which can develop secondary to COVID-19 infection. Materials and Methods: After applying the exclusion criteria, thorax computed tomography (CT) images of the remaining 1151 consecutive COVID-19 patients were evaluated. Calculation of MAC scores was done by two expert radiologists blinded to the study data. MI was defined as those with hs-TnI level (≥34 ng/dl). Patients included in the study were classified as having mortality and not occurring. Results: Male gender, advanced age (>65), hypertension, diabetes mellitus, chronic obstructive pulmonary disease, chronic kidney disease (CKD), coronary artery disease, heart failure and atrial fibrillation rates were statistically higher in the mortality group (p