Effects of Valproate, Carbamazepine, and Levetiracetam on the Antioxidant and Oxidant Systems in Epileptic Patients and Their Clinical Importance

Varoglu A. O., Yildirim A., Aygul R., Gundogdu Ö. L., Sahin Y. N.

CLINICAL NEUROPHARMACOLOGY, vol.33, no.3, pp.155-157, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 33 Issue: 3
  • Publication Date: 2010
  • Doi Number: 10.1097/wnf.0b013e3181d1e133
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.155-157
  • Keywords: antiepileptic drugs, paraoxonase, arylesterase, oxidized LDL, 8-hydroxyguanine, OXIDATIVE STRESS, SODIUM VALPROATE, ACID, DNA, MONOTHERAPY, DAMAGE
  • Recep Tayyip Erdoğan University Affiliated: No


Purpose: This study was carried out to determine the effects of valproate (VPA), carbamazepine, and levetiracetam (LEV) on antioxidant and oxidant enzyme activities and the clinical importance of these effects.