Effects of Valproate, Carbamazepine, and Levetiracetam on the Antioxidant and Oxidant Systems in Epileptic Patients and Their Clinical Importance


Varoglu A. O. , Yildirim A., Aygul R., Gundogdu Ö. L. , Sahin Y. N.

CLINICAL NEUROPHARMACOLOGY, vol.33, no.3, pp.155-157, 2010 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 33 Issue: 3
  • Publication Date: 2010
  • Doi Number: 10.1097/wnf.0b013e3181d1e133
  • Title of Journal : CLINICAL NEUROPHARMACOLOGY
  • Page Numbers: pp.155-157
  • Keywords: antiepileptic drugs, paraoxonase, arylesterase, oxidized LDL, 8-hydroxyguanine, OXIDATIVE STRESS, SODIUM VALPROATE, ACID, DNA, MONOTHERAPY, DAMAGE

Abstract

Purpose: This study was carried out to determine the effects of valproate (VPA), carbamazepine, and levetiracetam (LEV) on antioxidant and oxidant enzyme activities and the clinical importance of these effects.