Information technologies are an indispensable part of modern business, education, and personal lives. However, the COVID-19 pandemic has shown everybody around the world the insufficiency of available information technology infrastructures and the importance of establishing strong infrastructures for citizens from all backgrounds and geographic locations. The challenge has been especially hard for educational institutions because very few were truly prepared for an emergency transition to distance education. This chapter aims to explain the main components of a modern university information technology infrastructure and offer guidance in establishing a strong infrastructure for sustainable quality education.