Increased Epicardial Adipose Tissue in Patients with Isolated Coronary Artery Ectasia

Cetin M., ERDOĞAN T., KOCAMAN S. A., CANGA A., ÇİÇEK Y., DURAKOĞLUGİL M. E., ...More

INTERNAL MEDICINE, vol.51, no.8, pp.833-838, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 8
  • Publication Date: 2012
  • Doi Number: 10.2169/internalmedicine.51.7121
  • Journal Name: INTERNAL MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.833-838
  • Keywords: coronary artery ectasia, epicardial fat pad, epicardial adipose tissue, C-reactive protein, echocardiography, coronary angiography, BODY-MASS INDEX, PIGS IN-VIVO, CARDIOVASCULAR RISK, ADHESION MOLECULES, PERICARDIAL FAT, DISEASE, HEART, ATHEROSCLEROSIS, ASSOCIATION, EXPRESSION
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Background Epicardial adipose tissue (EAT), localized beneath the visceral pericardium, is a metabolically active endocrine and paracrine organ with possible interactions within the heart. Coronary artery ectasia (CAE) is a clinical entity characterized with localized or diffuse dilatation, of the coronary arteries, with a diameter of greater than 1.5 times that of adjacent segments. Although the etiopathogenesis is not clearly understood, some studies have revealed that CAE may be a form of atherosclerosis that has greater inflammatory properties than atherosclerosis. The goal of this study was to investigate whether EAT and the level of C-reactive protein (CRP) are increased in patients with isolated CAE compared to normal subjects.