Increased Epicardial Adipose Tissue in Patients with Isolated Coronary Artery Ectasia


Cetin M. , ERDOĞAN T. , KOCAMAN S. A. , CANGA A., ÇİÇEK Y. , DURAKOĞLUGİL M. E. , ...More

INTERNAL MEDICINE, vol.51, no.8, pp.833-838, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 8
  • Publication Date: 2012
  • Doi Number: 10.2169/internalmedicine.51.7121
  • Title of Journal : INTERNAL MEDICINE
  • Page Numbers: pp.833-838

Abstract

Background Epicardial adipose tissue (EAT), localized beneath the visceral pericardium, is a metabolically active endocrine and paracrine organ with possible interactions within the heart. Coronary artery ectasia (CAE) is a clinical entity characterized with localized or diffuse dilatation, of the coronary arteries, with a diameter of greater than 1.5 times that of adjacent segments. Although the etiopathogenesis is not clearly understood, some studies have revealed that CAE may be a form of atherosclerosis that has greater inflammatory properties than atherosclerosis. The goal of this study was to investigate whether EAT and the level of C-reactive protein (CRP) are increased in patients with isolated CAE compared to normal subjects.