Synthesis and characterisation of some new hybrid molecules containing thiophene, triazole and coumarin rings under microwave conditions

Yilmaz F.

JOURNAL OF CHEMICAL RESEARCH, no.7, pp.361-365, 2018 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: Issue: 7
  • Publication Date: 2018
  • Doi Number: 10.3184/174751918x15314831778603
  • Journal Name: JOURNAL OF CHEMICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.361-365
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

In this work, a new series of N'-{[4-amino-5-oxo-3-(thiophen-2-yl)-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetyl}-2-oxo-2H-1-benzopyran-3-carbohydrazides (thiophene-triazole-coumarin hybrid molecules) was synthesised from the reaction of 2-[4-amino-5-oxo-3-(thiophen-2-yl)-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetohydrazide and 3-(1H-benzotriazol-1-ylcarbonyl)-2H-chromen-2-ones by using microwave irradiation and conventional heating procedures and their results were compared. The reaction was performed using a very small amount of organic solvent and without using a catalyst.