Synthesis and antimicrobial properties of N-substituted derivatives of (E)-2 ',3 ''-thiazachalcones
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES, cilt.70, ss.45-50, 2015 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 70
- Basım Tarihi: 2015
- Doi Numarası: 10.1515/znc-2014-4182
- Dergi Adı: ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.45-50
- Recep Tayyip Erdoğan Üniversitesi Adresli: Evet
Özet
N-alkyl substituted 2',3 ''-thiazachalcones {3-[(1E)-3-(4-methylthiophene-2-yl)-3-oxoprop-1-en-1-yl]-1-alkyl (C-5-12,C-14) pyridinium bromides} were synthesized by a two-step reaction. The newly synthesized compounds were characterized by IR, H-1 NMR, C-13 NMR, elemental analysis and mass spectral studies. The synthesized compounds were tested for antibacterial activities and found to be more active against Gram-positive as compared to Gram-negative bacteria.