Effect of coronavirus disease-2019 infection on left atrial functions


ERGÜL E., Ozyildiz A., EMLEK N., Ozyildiz A., DUMAN H., ÇETİN M.

JOURNAL OF CARDIOVASCULAR ECHOGRAPHY, vol.32, no.2, pp.89-94, 2022 (Peer-Reviewed Journal) identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 2
  • Publication Date: 2022
  • Doi Number: 10.4103/jcecho.jcecho_83_21
  • Journal Name: JOURNAL OF CARDIOVASCULAR ECHOGRAPHY
  • Journal Indexes: Emerging Sources Citation Index, Scopus, EMBASE
  • Page Numbers: pp.89-94
  • Keywords: Coronavirus disease-2019, Left atrium, Left atrial functions, VENTRICULAR DIASTOLIC DYSFUNCTION, HEART-FAILURE, GREATER-THAN-OR-EQUAL-TO-65 YEARS, VOLUME, FRACTION, PRESSURE, UPDATE, IMPACT, SIZE, AGE

Abstract

Objective: Left atrial (LA) dysfunction is a crucial risk factor for cardiovascular events, and various pathologies may affect LA function. Coronavirus disease-2019 (COVID-19) is an ongoing global pandemic causing morbidity and mortality. In the present study, we aimed to evaluate LA functions in patients who recovered from COVID-19. Methods: Sixty consecutive patients recovered from COVID-19 and 60 healthy individuals as a control group were included in the study. Blood samples and echocardiography measurements were obtained from each subject. The two groups were compared in terms of demographic and echocardiographic characteristics. Results: In the COVID-19 group, LA maximum volume (LAVmax) (P = 0.040), LA pre-A volume (LAVpre-A) (P = 0.014), and LA active emptying fraction (P = 0.027) were higher, while LA passive emptying fraction (P = 0.035) was lower. In addition, left ventricular ejection fraction (P = 0.006) and isovolumetric relaxation time (P = 0.008) were decreased in this group. Although LA volume index was higher in the COVID-19 group, it does not reach statistical significance. Conclusion: LA functions may be impaired in patients recovered from COVID-19 infection.