Selenium or ozone: Effects on liver injury caused by experimental iron overload


Guevendi G. F. , EROĞLU H. A. , MAKAV M., Guvendi B., Adalre Y.

LIFE SCIENCES, cilt.262, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 262
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.lfs.2020.118558
  • Dergi Adı: LIFE SCIENCES

Özet

Aims: Iron is an important metal ion as a biocatalyst on the other hand iron overload causes various diseases. Iron overload can result in fibrosis and hepatocellular carcinoma with various pathophysiological mechanisms, including oxidative damage in the liver. Therefore; in this study the effects of ozone and selenium-whose antioxidant properties are known- were evaluated in liver injury induced by iron overload.