Enhanced MRI relaxivity of aquated Gd3+ ions by carboxyphenylated water-dispersed graphene nanoribbons


Gizzatov A., Keshishian V., Guven A., Dimiev A. M. , QU F., MUTHUPILLAI R., ...More

NANOSCALE, vol.6, no.6, pp.3059-3063, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 6 Issue: 6
  • Publication Date: 2014
  • Doi Number: 10.1039/c3nr06026h
  • Title of Journal : NANOSCALE
  • Page Numbers: pp.3059-3063

Abstract

The present study demonstrates that highly water-dispersed graphene nanoribbons dispersed by carboxyphenylated substituents and conjugated to aquated Gd3+ ions can serve as a high-performance contrast agent (CA) for applications in T-1- and T-2-weighted magnetic resonance imaging (MRI) with relaxivity (r(1,2)) values outperforming currently-available clinical CAs by up to 16 times for r(1) and 21 times for r(2).