(3,4-Dimethoxyphenyl)(2,3,4-trimethoxyphenyl)methanone was synthesized and its bromination was investigated in different conditions. Nine new products (bromophenol derivatives) were isolated in the reactions. These bromophenol derivatives were obtained by selective O-demethylation in its bromination with bromine. The products and their formations were discussed. (C) 2011 Elsevier Ltd. All rights reserved.