The development of ankylosing spondylitis in a patient with familial hemophilia


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Cüre O., İlkkılıç K.

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, cilt.26, sa.5, ss.954-956, 2023 (SCI-Expanded)

  • Yayın Türü: Makale / Vaka Takdimi
  • Cilt numarası: 26 Sayı: 5
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1111/1756-185x.14553.
  • Dergi Adı: INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.954-956
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Hemophilia is a rare inherited disease which causes bleeding due to Factor VIII or Factor IX deficiency. It is usually X-linked recessive and typically affects males. Arthropathy occurs as a result of cartilage damage and chronic synovitis due to recurrent intra-articular bleeding in hemophilic patients and is mostly seen in the knee, shoulder, hip and ankle joints. There are many other diseases that cause chronic synovitis ankylosing spondylitis (AS), which is a subtype of spondyloarthropathies that cause chronic low back pain, more common in men younger than 45 years of age. In addition to axial involvement, peripheral arthritis, uveitis, enthesitis and dactylitis can be seen. Although the etiology is not fully known, genetic and environmental factors are responsible for the pathogenesis. In this study, we aimed to present congenital hemophilia and AS coexistence in a 22-year-old male patient.