Increased Systemic Inflammatory Response with Mast Cell Activation In Elder Children With Cerebral Palsy

Demir C., Kilinc Y. B., Kilinc E.

CLINICAL AND EXPERIMENTAL HEALTH SCIENCES, vol.12, no.2, pp.294-301, 2022 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 2
  • Publication Date: 2022
  • Doi Number: 10.33808/clinexphealthsci.983877
  • Journal Name: CLINICAL AND EXPERIMENTAL HEALTH SCIENCES
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.294-301
  • Keywords: Cerebral palsy, Children, Inflammation, Mast cells, Cytokines, Gender, TUMOR-NECROSIS-FACTOR, NEONATAL CYTOKINES
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Objective: Increased systemic inflammatory response during intrauterine period or period before the age of 3 is associated with cerebral palsy (CP) pathogenesis; however, effects of inflammatory processes involving mast cell activation in elder children with CP remain unclear. We aimed to investigate the role of mast cells and proinflammatory cytokines in children with CP at 3-18 years of age.