Not only type 2 diabetes but also prediabetes is associated with portal inflammation and fibrosis in patients with non-alcoholic fatty liver disease


YILMAZ Y., Senates E., Yesil A., ERGELEN R., ÇOLAK Y.

JOURNAL OF DIABETES AND ITS COMPLICATIONS, vol.28, no.3, pp.328-331, 2014 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 3
  • Publication Date: 2014
  • Doi Number: 10.1016/j.jdiacomp.2014.01.013
  • Journal Name: JOURNAL OF DIABETES AND ITS COMPLICATIONS
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.328-331
  • Keywords: Prediabetes, Non-alcoholic fatty liver disease, Fibrosis, Clinical study, METABOLIC SYNDROME, GLUCOSE-TOLERANCE, STEATOHEPATITIS, NAFLD, PROGRESSION, PREVALENCE, BIOMARKERS, DIAGNOSIS, MARKER

Abstract

Aims: Growing evidence suggests that not only type 2 diabetes (T2D) but also prediabetes (PD) is common in patients with non-alcoholic fatty liver disease (NAFLD). However, few data exist on how PD impacts the histological characteristics of NAFLD patients. In this exploratory study, we sought to investigate the associations of PD and T2D with the severity of the histological features in patients with NAFLD.