The effect of acute organophosphate intoxication on female rat hippocampus cornu ammonis region pyramidal neuron numbers, biochemistry and morphology

BAŞ, ORHAN; ÇANKAYA, SONER; ENGİNYURT, ÖZGÜR; Aslan, Ali; Uydu, HÜSEYİN; Odaci, Ersan; YILMAZ, ALİ; Demir, ADEM; Gul, Tuba

doi:10.1016/j.jchemneu.2019.101652

The effect of acute organophosphate intoxication on female rat hippocampus cornu ammonis region pyramidal neuron numbers, biochemistry and morphology

BAŞ O., ÇANKAYA S., ENGİNYURT Ö., Aslan A., Uydu H. A., Odaci E., ...More

JOURNAL OF CHEMICAL NEUROANATOMY, vol.100, 2019 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 100
Publication Date: 2019
Doi Number: 10.1016/j.jchemneu.2019.101652
Journal Name: JOURNAL OF CHEMICAL NEUROANATOMY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Background: The most commonly used insecticides and pesticides worldwide are organophosphate compounds, chemicals that irreversibly inhibit the cholinesterase enzyme. Acute intoxication with cholinesterase inhibitors is known to cause permanent effects on both the human and rat brains.