The relationship between intracoronary thrombus burden and atherogenic index in patients with ST-elevation myocardial infarction

Emlek N., Duman H., Ogutveren M. M., Ergul E., Koc H., Durak H., ...Daha Fazla

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, cilt.26, sa.19, ss.7229-7235, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 19
  • Basım Tarihi: 2022
  • Doi Numarası: 10.26355/eurrev_202210_29915
  • Dergi Adı: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals
  • Sayfa Sayıları: ss.7229-7235
  • Anahtar Kelimeler: Thrombus burden, ST-elevation myocardial infarc-tion, Atherogenic index, PERCUTANEOUS CORONARY ANGIOPLASTY, DENSITY-LIPOPROTEIN, 000 PARTICIPANTS, RISK, DISEASE, THERAPY, ATHEROSCLEROSIS, METAANALYSIS, CHOLESTEROL, MECHANISMS
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

- OBJECTIVE: Increased coro-nary thrombus load is a strong predictor of ad-verse cardiovascular (CV) outcomes. Identifying predictors of intracoronary thrombus burden may contribute to the management of ST -seg-ment elevation myocardial infarction (STEMI). We aimed at evaluating the relationship between the atherogenic index (ATI) and coronary throm-bus burden in patients presenting with STEMI. PATIENTS AND METHODS: 139 patients who presented with STEMI and underwent prima-ry percutaneous coronary intervention were in-cluded in this study. Angiographic thrombus burden was classified as previously defined in the myocardial infarction (TIMI) study group. RESULTS: The patients were divided into two groups as those with high and low thrombus load. Independent predictors of high thrombus burden were ATI (OR: 4.23, 95% CI: 2.38-7.5; p < 0.001), serum creatinine level (OR: 17.4, 95% CI: 3.03-101.4; p=0.001) and non-LAD involve-ment (OR: 0.363, 95% CI: 0.14-0.92; p=0.034). The association of ATI with thrombus load was independent from HDL and TGL levels. CONCLUSIONS: The atherogenic index can be used as a reliable marker for increased coro-nary thrombus burden, which is associated with adverse CV outcomes.