Therapeutic proteins: A to Z


Özgür A., TUTAR Y.

Protein and Peptide Letters, vol.20, no.12, pp.1365-1372, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 12
  • Publication Date: 2013
  • Doi Number: 10.2174/092986652012131112125148
  • Journal Name: Protein and Peptide Letters
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1365-1372
  • Keywords: Insulin and erythropoietin, Interferons, Monoclonal antibodies, Recombinant DNA technologies, Therapeutic proteins
  • Recep Tayyip Erdoğan University Affiliated: No

Abstract

In recent years, therapeutic proteins have become an important growing class of drugs in the pharmaceutics industry. The development of recombinant DNA technology has caused to appreciation of therapeutic value of many proteins and peptides in medicine. Currently, approximately 100 therapeutic proteins obtained approval from Food and Drug Administration (FDA) and they are widely used in the treatment of various diseases such as cancer, diabetes, anemia and infections. This paper will summarize the production processes, pharmaceuticals and physicochemical properties and important classes of therapeutic proteins with their potential use in clinical applications. © 2013 Bentham Science Publishers.