Association between Omentin-1 and Coronary Artery Disease: Pathogenesis and Clinical Research.


Askin L., Duman H., Ozyıldız A., Tanriverdi O., Turkmen S.

Current cardiology reviews, vol.16, pp.198-201, 2020 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 16
  • Publication Date: 2020
  • Doi Number: 10.2174/1573403x16666200511085304
  • Journal Name: Current cardiology reviews
  • Journal Indexes: Emerging Sources Citation Index, Scopus, Agricultural & Environmental Science Database, Biotechnology Research Abstracts, EMBASE, MEDLINE
  • Page Numbers: pp.198-201
  • Keywords: Acute coronary syndrome, coronary artery disease, omentin-1, vascular smooth muscle cell, adipokines, adipose tissues, EPICARDIAL ADIPOSE-TISSUE, HIGH PLASMA OMENTIN, SERUM OMENTIN-1, RISK-FACTOR, ADIPOCYTOKINES, ISCHEMIA, ATRIAL, GENE

Abstract

Like other adipokines, omentin-1 is secreted from visceral adipose tissue and plays a vital role in the development of chronic inflammatory diseases, including cardiovascular events. Recent studies have shown that circulating omentin-1 levels are associated with various metabolic risk factors, such as high blood pressure, increased waist circumference, dyslipidemia, and glucose intolerance. The decrease in serum omentin level is an independent predictor of Coronary Artery Disease (CAD) and is associated with the severity of this disease. Since there is no relevant review in the literature, we aimed to summarize the studies on the relationship between omentin-1 and CAD.