Grisel's Syndrome: A Case Report

Beyazal M., Demirok D., ÇAPKIN E., USUL H., Tosun M., SARI A.

TURKISH JOURNAL OF RHEUMATOLOGY, vol.26, no.3, pp.243-247, 2011 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 3
  • Publication Date: 2011
  • Doi Number: 10.5606/tjr.2011.038
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.243-247
  • Keywords: Grisel's syndrome, neck pain, non-traumatic atlantoaxial subluxation, ATLANTOAXIAL SUBLUXATION, CHILDREN
  • Recep Tayyip Erdoğan University Affiliated: Yes


Grisel's syndrome is a non-traumatic atlantoaxial subluxation associated with inflammatory conditions of head and neck which occurs primarily in children. Increased flexibility of the ligaments during the inflammation is implicated in the pathogenesis of the subluxation between the axis and atlas. The diagnosis is made by clinical and radiological findings. In this article, we present a 19-year-old male patient who was admitted with a complaint of gradually increasing neck pain and stiffness. He had no history of trauma. Cervical spine radiography and computed tomography revealed atlantoaxial subluxation. Magnetic resonance imaging revealed subluxation and retropharyngeal soft tissue infection. Based on the clinical and radiological findings, we diagnosed the patient as having Grisel's syndrome, and the patient was treated with intravenous antibiotics and internal immobilization. Although the potential sequelae may be severe, early diagnosis and treatment of Grisel's syndrome can prevent tragic outcomes.