The Prognostic Significance of Soluble Urokinase Plasminogen Activator Receptor in Acute Myeloid Leukemia

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ERKUT N., MENTEŞE A., Ozbas H. M., Ermantas N., Sumer A., ÖREM A., ...More

TURKISH JOURNAL OF HEMATOLOGY, vol.33, no.2, pp.135-140, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 2
  • Publication Date: 2016
  • Doi Number: 10.4274/tjh.2014.0405
  • Journal Name: TURKISH JOURNAL OF HEMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.135-140
  • Keywords: Soluble urokinase plasminogen activator receptor, Acute myeloid leukemia, Prognosis, CANCER PATIENTS, COLORECTAL-CANCER, OVARIAN-CANCER, PLASMA, CELLS, TUMOR, SUPAR, EXPRESSION, SYSTEM, FORM
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Objective: The soluble urokinase plasminogen activator receptor (suPAR) is a soluble form of the urokinase plasminogen activator receptor expressed in various immune and cancer cells. The levels of suPAR have been demonstrated to correlate with prognosis in various cancers. This study was intended to investigate serum suPAR levels and their effect on prognosis in patients with acute myeloid leukemia (AML).